了解和减轻与成人重症监护病房患者伤害相关的药物错误:范围审查
Kathryn Puxty1, Margo van Mol2, María Cruz Martin Delgado3
1Department of Intensive Care, Glasgow Royal Infirmary, Glasgow, UK. kathryn.puxty@glasgow.ac.uk.
Intensive care medicine
|May 20, 2025
概括
药物错误在重症监护室 (ICU) 中很常见,但大多数在造成伤害之前就被发现了. 诸如电子处方和药剂师参与等干预措施可以减少错误和伤害患者.
科学领域:
- 关键护理医学 关键护理医学
- 患者安全 患者安全
- 药理学 药理学是指药理学的学科.
背景情况:
- 药物干预对于重症病患在重症监护室 (ICU) 中至关重要.
- 药物错误在ICU中很普遍,影响了患者的护理.
- 可预防的不良药物事件是重症监护机构的一个重大问题.
研究的目的:
- 绘制有关成年ICU中药物错误和可预防的不良药物事件的现有文献.
- 确定与ICU中药物错误相关的风险因素.
- 审查旨在减轻药物错误和不良药物事件的干预措施.
主要方法:
- 进行了全面的范围审查.
- 搜索了七个电子数据库,确定了2960个记录.
- 包括 48 个记录在数据提取选后.
主要成果:
- 由于研究设计异质,报告的药物错误和药物不良事件发生率的高变化.
- 确定了患者,临床,工作人员和环境风险因素,以及高风险药物.
- 严重或危及生命的伤害发生在1-5%的药物错误中,55%的干预集中在处方阶段.
结论:
- 大多数ICU药物错误都被系统和工作人员拦截,少数人造成伤害.
- 在电子处方,药物调和和临床药剂师活动中的决策支持有效地减少错误和对患者的伤害.
- 针对性干预,特别是在处方阶段,是提高ICU药物安全的关键.
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