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Updated: May 22, 2025

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

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解读使用重定位药物达里芬素B的Cathepsin B的治疗向

Sayantani Mukhopadhyay1, Thirukumaran Kandasamy2, Siddhartha S Ghosh1

  • 1IIT Guwahati: Indian Institute of Technology Guwahati, BSBE, INDIA.

ChemMedChem
|May 20, 2025
PubMed
概括

达里芬素作为一种重定向药物,在癌症中向甲素B (CTSB) 的药物显示出希望. 这项研究发现,它有效地抑制CTSB,诱导癌细胞死亡,并减少神经母细胞瘤和乳腺癌模型中的瘤进展标志物.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.卡瑟普辛B是B的类型之一.药物重用 药物重用神经母细胞瘤是一种神经母细胞瘤.瘤的球形状体

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