开发一种新的Cu-Mn氧化物层叠纳米片载药物,调节瘤微环境并增强抗瘤效应

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Updated: Apr 13, 2026

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
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Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles

Published on: August 2, 2016

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Xiaoying Shi1, Tianyi Shen1, Muge Gu1

  • 1Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China; National Key Laboratory of Innovative Immunotherapy, Shanghai Jiao Tong University, Shanghai 200240, China; Inner Mongolia Research Institute of Shanghai Jiao Tong University, China.

Journal of colloid and interface science
|May 20, 2025
PubMed
概括

这项研究开发了新的纳米级药物载体 (LDH/HA/DOX),可以精确地提供化疗,增强抗瘤效果并降低毒性. 该系统对瘤微环境进行了重新编程,以促进免疫细胞活动,以改善癌症治疗.

关键词:
这是一种抗瘤药物.化学动力学疗法是一种化学动力学疗法.两层 Cu-Mn 的双氧化物.德克索鲁比辛是一种多克索鲁比辛.免疫治疗是一种免疫疗法.

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