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Updated: May 22, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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纵向DNA甲基化和细胞类型比例的变化,在第一发精神病中对Risperidone治疗反应的改变

Vanessa Kiyomi Ota1, Leticia Maria Spindola2, Anne-Kristin Stavrum2

  • 1Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil; Departamento de Morfologia e Genética, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil.

Progress in neuro-psychopharmacology & biological psychiatry
|May 20, 2025
PubMed
概括

血液中的DNA甲基化 (DNAm) 可以预测在第一发精神病 (FEP) 中对RISPERIDONE治疗的反应. B细胞的减少与症状的改善相关,这表明DNAm是精神分裂症治疗监测的潜在生物标志物.

关键词:
抗精神病药物 抗精神病药物表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.甲基化 甲基化 甲基化里斯佩里胺是一种素.精神分裂症是一种精神分裂症.

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