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Updated: May 23, 2025

Methyl-binding DNA capture Sequencing for Patient Tissues
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CHIP的全表观基因组DNA甲基化关联研究为扰乱基因调节提供了洞察力

Sara Kirmani1,2, Tianxiao Huan3,4, Joseph C Van Amburg5

  • 1Framingham Heart Study, Framingham, MA, 01702, USA.

Nature communications
|May 20, 2025
PubMed
概括

克隆性血液形成 (CHIP) 涉及到老化血液干细胞的突变. 我们的研究揭示了与CHIP相关的表观遗传变化,增加了心血管疾病和死亡风险.

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