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Updated: May 23, 2025

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
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在小鼠中,ACSS2调解了一条表观遗传途径,以调节妊娠期间的β细胞适应

Yu Zhang1,2,3, Shuang He2,4, Xi Wang2,3

  • 1State Key Laboratory of Female Fertility Promotion, Department of Medical Genetics, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.

Nature communications
|May 20, 2025
PubMed
概括

孕产妇的胰腺β细胞通过涉及乙-A合成酶2 (ACSS2) 的表观遗传变化适应怀孕. 干扰,特别是高脂肪饮食,损害功能,但ACSS2删除可以恢复它,提供了关于妊娠糖尿病的见解.

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