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Updated: May 23, 2025

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
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An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

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一个超级通用的柔性体系统,使用乙烯以进行遗传代码重编程.

Yun-Kyu Choi1, Takayuki Katoh2, Adam Beattie1

  • 1Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.

Nature communications
|May 20, 2025
PubMed
概括

这项研究引入了一种新的柔性酶系统,使用烯酸来有效制备非蛋白质原性氨基酸tRNA (npAA-tRNA). 这种方法增强了库的构建,用于新型生物活性的开发.

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