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Updated: May 23, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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在功能相关基因的基因组多样性改变神经发育与瘤风险在具有生殖线PTEN变异的个体神经发育与瘤风险

Adriel Y Kim1,2, Lamis Yehia3, Charis Eng4,3,5,6,7,8

  • 1Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA. ayk31@case.edu.

NPJ genomic medicine
|May 20, 2025
PubMed
概括

患有PTEN变体 (PHTS) 的人面临癌症和神经发育障碍 (NDD) 的风险. 增加的同胞性或减少的基因组多样性可能解释这些不同的结果,影响炎症和细胞死亡途径.

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