患有精神疾病的个体患有视网膜疾病和视力损伤的风险
Jeffrey Chu1, Jacqueline K Shaia1,2, Hejin Jeong1
1Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Eye (London, England)
|May 20, 2025
概括
重度抑郁症和双相情感障碍增加了视网膜疾病的风险,而精神分裂症可能会降低. 视网膜疾病的精神病患者面临更高的视力损伤风险.
科学领域:
- 眼科医生 眼科 眼科
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 在精神疾病患者中注意到结构性视网膜变异.
- 精神疾病对视网膜疾病和视力损失风险的影响尚不清楚.
研究的目的:
- 评估被诊断患有精神疾病的个人视网膜疾病和视力损伤的风险.
主要方法:
- 一项回顾性队列研究,使用超过9500万个人的非识别EHR数据.
- 倾向性得分匹配 (PSM) 用于50-89岁的精神分裂症,双相情感障碍 (BD) 或主要抑郁症 (MDD) 患者.
- 分析视网膜疾病和视力障碍诊断,使用ICD-10代码和风险比计算.
主要成果:
- 精神分裂症的诊断与视网膜疾病的可能性较低有关.
- 双极性障碍和严重抑郁症的诊断与视网膜疾病的可能性更高有关.
- 与仅仅患有视网膜疾病的人相比,患有精神疾病和视网膜疾病的人患视力损伤的风险增加.
结论:
- 双极性障碍和严重抑郁症的诊断与视网膜疾病的可能性增加有关.
- 精神病患者同时患有视网膜疾病会增加视力受损的风险.
相关概念视频
Photoreceptors and Visual Pathways
5.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.5K
The Retina
66.9K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
66.9K
Anatomy of the Eyeball
5.9K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
5.9K


