从1990年到2021年,多囊性卵巢综合征的全球负担的变化
Tong Lin1, Bingqin Xie2, Juan Yang1
1Department of Traditional Chinese Medicine, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Reproductive health
|May 20, 2025
概括
自1990年以来,多囊性卵巢综合征 (PCOS) 的流行和发病率在全球范围内显著增加. 高社会人口指数地区的PCOS负担更大,特别是在年轻女性中.
科学领域:
- 内分泌学 在内分泌学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 多囊性卵巢综合征 (PCOS) 是一种复杂的内分泌疾病,对无排卵不育有显著的贡献.
- 表观遗传和环境因素在PCOS发展中发挥着作用.
- 了解PCOS的全球负担对于公共卫生倡议至关重要.
研究的目的:
- 分析从1990年到2021年的全球,区域和国家PCOS负担.
- 为了确定PCOS发病率,患病率和残疾调整寿命年 (DALYs) 的趋势.
- 根据年龄和社会人口指数 (SDI) 检查PCOS负担的变化.
主要方法:
- 利用了2021年全球疾病负担研究 (GBD 2021) 的数据.
- 包括204个国家和21个地区的发病率,流行率和DALY数据.
- 分析了不同年龄组和SDI水平的年龄标准化率和趋势.
主要成果:
- 从1990年到2021年,全球年龄标准化PCOS发病率和患病率分别增加了超过26%和28%.
- 在全球范围内,PCOS的年龄标准化DALY也上升了27.58%.
- 患病率在15-19岁的女性中达到顶峰,在高SDI地区和意大利,日本和新西兰等国家/地区的患病率最高.
结论:
- 全球PCOS的负担正在增加,需要紧急的公共卫生干预措施.
- 在各个年龄组和SDI地区,PCOS负担存在显著差异.
- 需要有针对性的干预和政策来应对PCOS带来的日益严重的公共卫生挑战.
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