代谢综合征和膀癌风险:综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合综合
Yi Yuan1, Tongpeng Liu1, Yu Yao1
1Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
BMC urology
|May 20, 2025
概括
代谢综合征 (MetS) 增加了膀癌 (BC) 的风险,特别是糖尿病,低HDL和高甘油三. 这项研究分析了全球研究趋势,并对11项研究进行了元分析,以证实这些关联.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢障碍 代谢障碍 代谢障碍
- 在瘤学瘤学.
- 图书统计学 图书统计学
- 流行病学 流行病学
背景情况:
- 代谢综合征 (MetS) 是一组增加心脏病,中风和糖尿病风险的疾病.
- 膀癌 (BC) 是一个重要的全球健康问题.
- MetS和BC风险之间的关系需要进一步进行全面的调查.
研究的目的:
- 对全球关于MetS和BC的研究进行文献计量分析.
- 确定研究趋势,热点和该领域的关键贡献者.
- 进行元分析,评估MetS及其组件与BC风险之间的关联.
主要方法:
- 来自Web of Science核心集合的147篇论文 (2002-2022) 的图书统计分析.
- 来自PubMed,Embase和Cochrane图书馆的11项研究 (665,164名患者) 的元分析.
- 我使用了VOSviewer,R包"bibliometrix"和RevMan 5.4进行分析.
主要成果:
- MetS与显著更高的BC风险相关 (OR=1.62,P<0.01).
- 特定的MetS成分,如糖尿病 (OR=0.44,P<0.01),低HDL (OR=0.29,P<0.01) 和高甘油三 (OR=0.59,P<0.01) 显示与BC风险有显著的关联.
- 在本分析中,高血压和肥胖与BC风险没有显著关联.
结论:
- 甲状腺素和某些成分 (糖尿病,低HDL,高甘油三) 与膀癌的风险增加有关.
- 图书统计分析突出了MetS和BC的研究趋势和合作.
- 调查结果强调了为BC预防策略管理MetS的重要性.
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