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Updated: May 22, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

179

双响应免疫调节RNAi纳米平台,用于有效的免疫检查点阻塞和增强癌症免疫治疗

Yuan Cao1,2,3, Zixuan Zhao1,4, Junyue Fang1,2,3

  • 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.

Advanced healthcare materials
|May 21, 2025
PubMed
概括

这项研究开发了一种双响应纳米平台,结合甲胺和siRNA来增强癌症免疫疗法. 纳米平台沉默PD-L1,激活AMPK,并重塑瘤免疫微环境,以改善乳腺癌治疗.

关键词:
它们是RNAiRNAi.癌症免疫疗法免疫疗法双响应式的 双响应式甲胺前药物是什么意思这是一个纳米平台.

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