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Updated: May 22, 2025

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
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在瘤学药物开发中的剂量优化:营销后要求和承诺的风险因素

Hiroe Kitagaki1,2, Kentaro Takeda3, Kazuya Murai1,4

  • 1Regulatory Science, Graduate School of Pharmaceutical Science, Meiji Pharmaceutical University, Tokyo, Japan.

Clinical pharmacology and therapeutics
|May 21, 2025
PubMed
概括

乐观计划指导瘤学药物剂量,但这项研究确定了风险. 在最大耐受水平下剂量增加不良事件和批准后剂量优化需求,为更好的早期试验设计提供信息.

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