鼻粘膜皮质瘤癌的生存分析和预后因素
Yuting Lai1, Xiaole Song1,2, Huankang Zhang1
1ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Ear, nose, & throat journal
|May 21, 2025
概括
鼻粘膜皮质癌 (NPMEC) 患者的生存率较好. 淋巴转移和T阶段影响无进展生存,而淋巴转移影响整体生存.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 癌症研究 癌症研究
背景情况:
- 鼻粘膜皮质癌 (NPMEC) 是一种罕见的恶性瘤.
- 了解生存结果和预后因素对于患者管理至关重要.
研究的目的:
- 调查NPMEC患者的生存率.
- 在NPMEC中确定影响整体生存 (OS) 和无进展生存 (PFS) 的预后因素.
主要方法:
- 对57名NPMEC患者的回顾性审查 (19名来自中心,38名来自文献).
- 卡普兰-梅尔法和LOG-rank测试用于OS和PFS分析.
- 多变量生存分析的考克斯回归模型.
主要成果:
- 五年后的OS和PFS率分别为62.8%和51.3%.
- 淋巴转移严重影响了OS和PFS.
- T阶段影响PFS,并结合治疗显示PFS的独立改善.
结论:
- 一般来说,NPMEC患者的长期存活率很好.
- 淋巴转移是OS和PFS的独立预测因素.
- T阶段和治疗方式是PFS的独立预测因素.
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