1999年至2024年纳米材料和肝细胞癌的研究趋势:图书识别分析
Mao-Sheng Liu1, Si-Si Zhong2, Jin-Ke Wang1
1Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Drug design, development and therapy
|May 21, 2025
概括
纳米材料在诊断和治疗肝癌 (肝细胞癌,HCC) 方面表现有前途. 研究趋势侧重于向疗法,光动力疗法和瘤微环境,包括纳米疫苗等新兴策略.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术纳米技术
- 在瘤学瘤学.
背景情况:
- 纳米材料为诊断和治疗肝细胞癌 (HCC) 提供了潜力.
- 重要的研究已经探索了它们在HCC管理中的应用.
研究的目的:
- 分析纳米材料研究中的演变和趋势,使用图库分析分析HCCC.
- 确定关键的研究热点,有影响力的机构和新兴战略.
主要方法:
- 从Web of Science数据库中对1617个英语出版物的图书法分析 (1999-2024年).
- 使用VOSviewer和Citespace软件进行数据提取,统计分析和可视化.
主要成果:
- 从2012年开始,出版量迅速增加,在2020年达到顶峰.
- 中国在出版物方面领先;美国在引用方面领先.
- 关键的研究领域包括针对性药物输送,治疗和HCC的成像.
- 新兴的策略包括纳米疫苗,纳米抗体和协同疗法.
- 尽管进行了临床试验,但尚未报告使用纳米材料进行HCC治疗的重大突破.
结论:
- 对HCC纳米材料的研究表明上升趋势.
- 目前的领域重点是纳米粒子向化疗,光动力疗法和瘤微环境研究.
相关概念视频
Targeted Cancer Therapies
7.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.0K
Liver Regeneration
4.1K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
4.1K


