在接受EUS导向胃肠口术和肠腔支架安置的患者之间对胃空化的比较分析:试点分析试点分析
Sridhar Sundaram1, Ameya Puranik2, Akhil Mahajan1
1Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Mumbai, India.
与肠道支架 (ES) 相比,内超声导向胃肠静脉切除术 (EUS-GE) 在胃出口阻塞的患者中显示了改善的胃排空. 这表明EUS-GE提供了超越长期结果的短期临床益处.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 医疗成像医学成像
背景情况:
- 内镜超声导向胃肠静脉切除术 (EUS-GE) 是胃口支架 (ESs) 的可行替代方案,用于胃口出口阻塞.
- 之前的研究表明,EUS-GE在长期临床成功和减少重新干预率方面的优势.
- 在ES安置后胃和瘤侵占可能会损害胃排空.
研究的目的:
- 为了比较EUS-GE和ES之间的短期胃空化.
- 评估EUS-GE对ES的直接功能性益处.
主要方法:
- 一项试点研究包括接受ES或EUS-GE用于胃出道阻塞息的患者.
- 在手术后2周,使用标有Tc-Sulphur的半固体食物来评估胃空气.
- 主要结局是胃的半排空时间 (t1/2).
主要成果:
- 与ES (t1/2: 118分钟) (P=0.02) 相比,EUS-GE表现出明显更快的胃排空 (t1/2: 72分钟).
- 异常胃排空发生在EUS-GE患者中只有5.3%,而ES患者中只有47.6% (P=0.004).
- 两周后的临床成功和六个月后的重新干预没有显著差异.
结论:
- 与ES相比,EUS-GE与更高的胃排空有关.
- 这种改善的胃排空表明EUS-GE.的潜在短期临床优势.
- EUS-GE可能会提供超出已确定的长期成果的好处.
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