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Updated: May 23, 2025

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

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帕奇米酸通过PPARα抑制铁化,减轻与代谢功能障碍相关的脂肪性肝病

Guilin Ren1,2, Yiyou Lin1,2, Jiannan Qiu1,2

  • 1School of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Frontiers in pharmacology
|May 21, 2025
PubMed
概括

帕奇米酸 (Pac) 通过减少肝脏脂肪和损伤,有效治疗与代谢功能障碍相关的脂肪性肝病 (MASLD). 它通过抑制MAPKs途径和调节PPARα而起作用,为MASLD提供了一种新的治疗方法.

关键词:
MAPKs 信号通路的信号通道这是一种PPARα.铁性化 (ferroptosis) 是一种与代谢功能障碍相关的脂肪性肝病.帕奇米酸是什么 帕奇米酸

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