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Updated: May 23, 2025

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
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过度伸展会导致血管光滑肌肉细胞中的脂质积累,这些细胞依赖NADPH氧化酶1的作用

Jiazhen Zhang1, Qinfen Li1, Suoqi Ding2

  • 1College of Life Sciences, University of Chinese Academy of Sciences, Beijing 101408, China.

Mechanobiology in medicine
|May 21, 2025
PubMed
概括

脉动动脉拉伸促进血管光滑肌细胞 (VSMC) 脂质积累和泡细胞的形成,通过上调NOX1. 抑制NOX1或活性氧物种 (ROS) 阻止了这一过程,揭示了动脉样硬化的新机制.

关键词:
动脉样硬化是一种动脉样硬化.脂质的积累 脂质的积累在NADPH氧化酶1中.过度伸展 过度伸展血管光滑肌细胞是血管光滑肌细胞

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