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Updated: May 23, 2025

Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics
11:40

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Published on: June 23, 2022

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在 lysosomal 光层内,LAMP2A 的双域架构调节了它与 HSPA8/Hsc70 的相互作用

Yuta Ikami1,2, Kazue Terasawa2, Tetsuro Watabe2

  • 1Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan.

Autophagy reports
|May 21, 2025
PubMed
概括

伴侣介导的自包括溶酶体关联膜蛋白2A (LAMP2A) 和热冲击蛋白8 (HSPA8). 这项研究揭示了LAMP2A和HSPA8之间的直接相互作用,澄清了它们在蛋白质降解中的作用.

关键词:
陪伴者介导的自细胞.在HSPA8中,HSPA8是HSPA8标准.在LAMP2A中,使用LAMP2A扩展的遗传代码.网站特定的照片交叉链接特定地点的固体阻碍物.

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