疫情环境中奇孔尼亚病毒的阳性,印度:系统性审查和元分析
Ramya Nagarajan1, Mogan Kaviprawin2, Lavanya Ayyasamy2
1Non-Communicable Division, Indian Council of Medical Research-National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Journal of family medicine and primary care
|May 21, 2025
概括
印度的 Chikungunya 病毒 (CHIKV) 疫情显示出高血清阳性,表明社区疾病负担很大. 虽然血清流行率已经下降,但对 chikungunya 疫情的持续警仍然至关重要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 自2005年以来, Chikungunya病毒 (CHIKV) 在印度引起了众多疫情.
- 在社区爆发期间的疾病动态尚不清楚.
研究的目的:
- 在印度社区爆发期间估计奇孔古尼亚感染的血清阳性.
- 了解疾病负担和传播模式.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 包括18篇文章报告了印度社区爆发中CHIKV血清阳性.
- 提取了关于年份,地点,诊断测试和评估研究质量的数据.
主要成果:
- chikungunya 感染的综合血清阳性为 38% (95% CI: 30-45%).
- 血清阳性在男性 (41%) 和女性 (41%) 中是相似的.
- 在印度南部 (48%) 和东部 (45%) 观察到更高的阳性.
结论:
- 奇孔古尼亚在印度爆发环境中表现出高血清阳性,这意味着大量的社区疾病负担和当地传播.
- 尽管血清发病率随着时间的推移而下降,但对潜在疫情的持续监测至关重要.
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