在有或没有全身性红血性狼的孕妇中感染易感性
Hiba I Khogali1, Aaesha M Alhebsi2, Meera A Altamimi2
1Department of Rheumatology, Tawam Hospital, Al Ain, UAE.
Lupus
|May 21, 2025
概括
患有全身性红斑狼 (SLE) 的孕妇面临明显更高的感染风险和不良结果. 研究发现,怀孕期间使用氧化可以降低这些高风险怀孕的感染易感性.
科学领域:
- 产科和妇科 产科和妇科
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 系统性红斑狼 (SLE) 是一种自身免疫性疾病,主要影响女性,在怀孕期间构成风险.
- 关于SLE孕妇感染率的数据有限.
- 了解感染易感性对于管理母亲和胎儿健康至关重要.
研究的目的:
- 评估SLE和没有SLE的妇女在怀孕期间感染风险.
- 确定影响孕妇SLE患者感染易感性的因素.
- 为了评估患有SLE的妇女的怀孕结果.
主要方法:
- 来自阿联塔瓦姆医院 (2010-2023) 的医疗记录的回顾性队列分析.
- 包括有SLE和怀孕的阿联妇女,与没有SLE的年龄匹配对照相比.
- 单变量和多变量回归分析以确定感染风险因素.
主要成果:
- 在SLE组中,感染率更高 (54.7%与29.8%相比),胎儿不良结果 (48.3%与24.2%相比) 和母亲的结果 (71.3%与43%相比).
- 呼吸道感染是最常见的.
- 怀孕期间使用氧化与感染风险降低有关.
结论:
- 与非SLE人口相比,患有SLE的孕妇具有显著增加的感染风险和不良结果.
- 氧化是减轻SLE患者怀孕期间感染风险的关键因素.
- 针对性干预和多学科护理对于改善SLE妇女怀孕结果至关重要.
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