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运动神经转移用于自愿生理空气:科学基础,历史审查和病例报告
Justin M Brown1, Elise De2, Benjamin R Johnston3
1Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Neurosurgery
|May 21, 2025
概括
人体运动神经被手术转移到膀中,以恢复膀的内脏,恢复功能性排空的detrusor激活. 这种新的神经转移程序证明了在患有十字神经损伤的患者中,膀重新内脏化和意志控制的成功.
科学领域:
- 神经外科 神经外科
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 再生医学是一种再生医学.
背景情况:
- 神经神经损伤可能导致膀功能丧失.
- 在神经受伤后,正在探索手术干预以恢复膀控制.
研究的目的:
- 报告人体运动神经的手术转移到自主目标神经的情况.
- 为了恢复功能空白的detrusor激活.
- 详细介绍手术及其两年临床结果.
主要方法:
- 一位患有膀功能障碍的患者由于圣神经根切除而经历了双边神经移植.
- 阻塞神经的一部分被用来通过下部胃下来重新灌输膀.
- 功能和神经生理学评估是在两年内进行的.
主要成果:
- 膀充满的感觉在移植后6个月恢复.
- 由尿动力学研究证实的自发性膀收缩在12个月后实现.
- 通过大腿引和坐来实现尿流,激活闭关神经.
结论:
- 这种新型的神经转移成功地重定向了体质轴突,以激活膀,以便自愿排空.
- 这项研究为基于神经转移的膀恢复提供了临床概念证明.
- 支持进一步开发神经传输技术,以帮助患有斜骨缩的患者.
相关概念视频
01:26The Micturition Reflex
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Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
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01:23Urinary Bladder
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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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