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Updated: Jul 14, 2026

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
12:22

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers

Published on: January 22, 2013

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在清细胞细胞癌中进行代谢重编程和免疫微环境分析:对预后,向治疗和耐药性的影响

Xiao Zheng1, Yongqiang Liu1, Zixin Yang2

  • 1Department of Nephrology, Gezhouba Central Hospital of Sinopharm, The Third Clinical Medical College of China Three Gorges University, Yichang, 443002, Hubei, China.

Discover oncology
|May 21, 2025
PubMed
概括

这项研究揭示了清细胞细胞癌 (ccRCC) 患者的独特代谢概况,将代谢活动与生存和免疫反应联系起来. 这些发现有助于开发个性化的ccRCC治疗方法.

关键词:
清细胞脏细胞癌.免疫微环境是一个微环境.代谢途径 代谢途径个性化治疗是个性化的治疗.预测生物标志物预测生物标志物

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...