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中国汉族青少年和儿童肘部关节X射线的骨年龄估计基于多个深卷积神经网络模型
Dan-Yang Li1,2,3, Hui-Ming Zhou3,4, Lei Wan3
1Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030000, China.
Fa yi xue za zhi
|May 21, 2025
概括
深度学习使用肘部X射线准确估计了中国儿童的骨龄. 使用与UNet++和DenseNet121模型的完整联合细分可以显著提高估计准确性.
科学领域:
- 放射学 放射学是一门学科.
- 人工智能的人工智能
- 儿科内分泌学 儿科内分泌学
背景情况:
- 准确的骨龄估计对于评估儿童骨成熟度至关重要.
- 传统的方法可能是主观和耗时的.
- 深度学习为自动化和客观的骨年龄评估提供了潜力.
研究的目的:
- 开发和评估一个深度学习模型,从肘部X射线图像中自动估计骨龄.
- 为了比较不同的细分策略来优化模型性能.
- 在中国儿科人口中评估模型的准确性.
主要方法:
- 利用了943张6至16岁的汉族儿童的肘部X射线图像.
- 我们比较了三个方案:直接输入,用关键骨标注进行细分,用全骨标注进行细分.
- 使用U-Net,UNet++,TransUNet进行细分和各种CNN (VGG,Inception,ResNet,DenseNet) 进行回归.
- 在内部 (189张图像) 和外部 (104张图像) 测试套件上验证了模型.
主要成果:
- UNet++实现了高细分精度 (93.8%),并提供完整的联合注释 (图3).
- 采用方案3的DenseNet121模型在内部测试集中表现最好 (MAE:0.83年).
- 在外部测试组中,使用方案3的DenseNet121实现了0.89年的MAE和1.00年的RMSE.
结论:
- 使用UNet++进行细分和DenseNet121进行回归的深度学习方法对骨年龄的估计有效.
- 细分整个肘部关节 (遥远的膀臂,近距离半径,近距离肘部) 可以提高准确性.
- 这种自动化方法在临床实践中对客观骨年龄评估有希望.
相关概念视频
01:18Classification of Bones
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...
01:15Bones of the Upper Limb: Ulna
The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side of the...
01:09Changes in the Appendicular Skeleton with Age
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...