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Updated: May 23, 2025

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation
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CD83抑制了内源的March-I依赖的MHCII类无化,内细胞化和降解

Sunil Kaul1, Nelson B Cole1, Joanna Bandola-Simon1

  • 1Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Proceedings of the National Academy of Sciences of the United States of America
|May 21, 2025
PubMed
概括

E3泛基因酶March-I调节了抗原呈现细胞上的主要基因相容性复合体II类 (MHC-II) 周转率. CD83还抑制了March-I活动,揭示了对免疫反应调节的新见解.

关键词:
在MHCII类中,MHC是II类.抗原呈现的呈现方式.无处不在的化

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