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Updated: May 23, 2025

Measuring Microbial Mutation Rates with the Fluctuation Assay
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Published on: November 28, 2019

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微卫星稳定的结直肠癌中DNA突变率的异质性和演变

Elena Grassi1,2, Valentina Vurchio1,2, George D Cresswell3,4

  • 1Department of Oncology, University of Torino, 10060 Candiolo, Torino, Italy.

Science translational medicine
|May 21, 2025
PubMed
概括

大肠直肠癌 (CRC) 的DNA突变率并不统一. 这项研究揭示了患者衍生的瘤中明显的,可遗传的突变率足迹,转移性CRC的比率更高,突出了癌症进展中的DNA突变不稳定性.

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