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Updated: May 23, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

Published on: July 25, 2019

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单分子分析揭示了通过变异PRC1复合体的染色质无处不在的机制

Alexandra Teslenko1, Beat Fierz1

  • 1SB ISIC LCBM, École Polytechnique Fédérale de Lausanne (EPFL), Station 6, CH-1015 Lausanne, Switzerland.

Science advances
|May 21, 2025
PubMed
概括

变种多组复合抑制复合体1 (PRC1) 酶调节基因转录. 这项研究揭示了PRC1复合体如何与染色质动态相互作用以至于无处不在的基因组,从而确定亚型特异性活性.

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