在中国和全球的类风湿性关节炎负担的趋势,1990-2021年:基于GBD数据库的纵向研究
Zhengpeng Li1, Hao Zeng1, Bo Jin1
1Guangxi University of Chinese Medicine, Nanning, China.
PloS one
|May 21, 2025
概括
风湿性关节炎 (RA) 的发病率和流行率在全球范围内不断上升,特别是在中国,特别影响女性和老年人. 虽然死亡率有所下降,但积极的干预措施对于管理这种日益增长的慢性自身免疫性疾病负担至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 风湿性关节炎 (RA) 是一种慢性自身免疫性疾病,具有重大的全球健康和经济影响.
- 包括中国在内的发展中国家面临着由RA造成的重大负担.
研究的目的:
- 分析1990年至2021年在中国和全球的RA发病率,流行率,死亡率和残疾调整寿命年 (DALYs) 的趋势.
- 确定RA疾病负担中的人口差异和与年龄相关的趋势.
主要方法:
- 利用全球疾病负担 (GBD) 数据库对RA数据进行了分层,分年龄,性别和时期.
- 员工联合点回归程序用于计算趋势分析的年平均百分比变化 (AAPC).
- 通过严格的选和对比,确保数据的准确性和可比性.
主要成果:
- 在中国和全球范围内,RA的发病率和流行率有所增加;中国的病例增加了133%.
- 全球和中国的死亡率 (ASMR) 和因残疾调整的寿命年数 (ASDR) 均下降.
- 女性和老年人 (45岁以上) 呈现出更高的RA负担,发病率和流行率.
结论:
- 由于人口老龄化和生活方式的变化,RA的负担正在增加,女性更容易受到影响.
- 尽管死亡率降低,但发病率和流行率的上升需要加强早期查,个性化治疗和针对妇女和老年人提供有针对性的支持.
- 促进健康的生活方式和改善医疗保健服务对于减轻RA的健康和社会经济影响至关重要.
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