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计算机化抑制控制训练对短睡眠时间表型失眠的益处和神经机制:rs-fMRI研究

Haobo Zhang¹, Zhangwei Lv¹, Hanfei Chen¹

¹Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, 400715, China; Key Laboratory of Cognition and Personality (Southwest University), Ministry of Education, Chongqing, 400715, China.

Behaviour research and therapy

|May 21, 2025

概括

计算机化抑制控制 (IC) 训练改善了短睡眠时间 (ISSD) 失眠障碍的睡眠质量. 这种干预措施增强了与睡眠调节相关的前额叶区域的大脑功能.

科学领域:

神经科学是一个神经科学.
睡眠医学睡眠医学
认知心理学认知心理学

背景情况:

抑制性控制 (IC) 障碍是短睡眠持续时间 (ISSD) 失眠障碍的标志.
IC在调节睡眠-清醒周期方面发挥着至关重要的作用.
本研究研究了IC培训作为ISSD的潜在治疗方法.

研究的目的:

评估计算机化IC培训在改善ISSD患者睡眠方面的有效性.
通过使用休息状态fMRI (rs-fMRI) 探索IC训练后睡眠改善的基础神经机制.

主要方法:

20名ISSD患者接受了为期3周的计算机化IC培训计划.
通过主观 (PSQI,ISI) 和客观 (EEG) 的措施来评估睡眠质量.
rs-fMRI用于分析与IC相关的大脑区域区域区域同质性 (ReHo),fALFF和功能连接性 (FC) 的变化.

主要成果:

计算机化IC培训显著改善了ISSD患者的主观和客观睡眠质量.
神经成像显示左侧MOFC的ReHo增加,右侧MFG的fALFF增加.
在MOFC和右RG之间增强的FC与睡眠改善相关.

结论:

计算机化IC培训是改善ISSD睡眠的有效干预措施.
这种治疗可能通过诱导前额叶皮层区域的功能变化来改善睡眠.
需要进一步的研究来评估IC针对性干预对ISSD的长期影响.

关键词:

计算机化的培训培训.抑制性控制是一种抑制性控制.失眠障碍是一种失眠障碍.静止状态功能磁共振成像技术睡眠时间短的表型睡眠时间短的表型

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