临床特征 与精神病患者的功能性发作相关的临床特征
Allison M Lake1, India A Reddy2, Robert Havranek3
1Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Schizophrenia research
|May 21, 2025
概括
功能性发作 (FS) 在精神病患者中更为常见,这表明存在显著的关联. 这些患者还经历了更高的自杀倾向率,白内障,以及医疗保健利用率的增加.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 功能性 (FS) 是类似于的事件,但没有异常的大脑电活动.
- 以前关于FS和精神病之间的联系的研究已经产生了不一致的结果.
- 这项研究调查了FS和精神病之间的关联,以及它对患者结果的影响.
研究的目的:
- 为了确定功能性 (FS) 是否在精神病患者中更为普遍.
- 探索FS如何影响精神病患者的临床特征,死亡率和医疗保健资源利用率.
主要方法:
- 利用了761,848名个人 (1989-2023) 的电子健康记录.
- 在5,219名精神病患者中分析了FS与精神病结果,性创伤,医疗保健使用和并发症之间的关联.
主要成果:
- 患有精神病的患者患FS的几率明显更高 (OR = 10.09).
- 在精神病患者中,FS与增加的自杀倾向,白内障,性创伤史和更多抗精神病药物试验有关.
- 同病性FS与更高的医院出院频率相关. 精神病后的诊断.
结论:
- 功能性发作在精神病患者中更为常见.
- FS与自杀倾向,白内障和精神病/医疗并发症率的增加有关.
- 患有并发性FS的患者表现出医疗保健利用率的增加.
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