短暂的射精禁欲是否会改善无法解释不育症的夫妇的子宫内受精结果? 一个队列研究研究
Hemapriya Mohan1, Parimala Chinta1, Ann Margaret Mangalaraj1
1Department of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, India.
概括
对于宫内授精 (IUI) 周期,射精禁欲的持续时间不会显著影响未解释不育的夫妇的活产率. 与标准或更长时间的禁欲期相比,更短的禁欲期不会改善结果.
科学领域:
- 生殖医学 生殖医学
- 不孕症治疗 不孕症治疗
- 辅助生殖技术 辅助生殖技术
背景情况:
- 宫内授精 (IUI) 是一种常见的生育治疗方法.
- 在IUI之前,射精禁欲的最佳持续时间尚未确定.
- 了解这一因素可能会提高IUI成功率.
研究的目的:
- 研究IUI周期中射精禁欲的持续时间与活产率之间的关联.
- 为了确定更短的禁欲期 (≤2天) 是否提供了优势.
主要方法:
- 追溯性队列研究,对573个IUI周期的不解释不育的夫妇进行研究.
- 根据禁欲持续时间,周期被分为三个组:≤2天,3-7天和>7天.
- 主要结局是每个周期的活产率;次要结局包括怀孕和流产率.
主要成果:
- 每个周期的活产率为9.6% (≤2天),9.3% (3-7天) 和18.8% (>7天),没有统计学上显著的差异 (p=0.230).
- 临床怀孕率也在各组之间是可比的 (11.7%,12.0%,18.8%;p=0.474).
- 经过调整后的分析证实,禁欲持续时间与活产率之间没有显著的关联.
结论:
- 对于因无法解释的不孕症而接受IUI的夫妇来说,射精禁欲的持续时间不会显著影响活产率.
- 与标准或长期戒断相比,更短的禁欲期≤2天并不能提高成功率.
- 目前关于IUI前禁欲持续时间的建议可能不需要根据这一发现进行修改.
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