慢性睡眠碎片化的心血管后果:来自阻塞性睡眠呼吸暂停实验模型的证据

Mohammad Badran1, Clementine Puech2, David Gozal3

  • 1Department of Pediatrics, University of Missouri, Columbia, MO, USA; Department of Medical Physiology and Pharmacology, University of Missouri, Columbia, MO, USA.

Sleep medicine
|May 21, 2025
PubMed
概括

慢性睡眠碎片化 (SF) 独立导致心血管问题,如高血压和阻塞性睡眠呼吸暂停 (OSA) 中的动脉硬. 这项研究强调了SF作为OSA相关心脏风险的关键驱动因素,并提出了新的治疗目标.

相关概念视频

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
120
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
125
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K