最近被诊断患有2型糖尿病的个体体的体力活动和白尿
T Norlén1, T B Olesen2, S L Domazet3
1Steno Diabetes Center Odense, Odense University Hospital, Odense C, Denmark.
在2型糖尿病患者中,较高的中度至强度体力活动 (MVPA) 与较少的白蛋白尿有关. 这项研究发现,MVPA在基线时与白尿存在和发病率的几率较低有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 运动生理学 运动生理学
背景情况:
- 2型糖尿病是一个日益严重的全球健康问题.
- 白蛋白尿是糖尿病病的关键指标.
- 对身体活动的客观测量对于理解其影响至关重要.
研究的目的:
- 检查新诊断的2型糖尿病患者客观测量的体力活动和白蛋白尿之间的关系.
- 评估中度至强度体力活动 (MVPA) 和久坐时间如何影响白尿的存在和发展.
主要方法:
- 利用了丹麦战略研究中心2型糖尿病队列832名参与者的数据.
- 在基线和4年随访时使用加速计评估MVPA和久坐时间.
- 通过逻辑回归来研究与白蛋白尿的相关性 (UACR ≥30 mg/g).
主要成果:
- 发现基线MVPA与白尿的存在 (OR:0.82) 和发病率 (OR:0.74) 之间的反向关联.
- 久坐不动的时间与白尿发育没有显著的关联.
- 在4年内,对于MVPA或久坐时间的变化没有发现显著的关联.
结论:
- 基线中度至强度的体力活动与最近被诊断为2型糖尿病的个体的白蛋白尿相反相关.
- 虽然MVPA的增加暗示了较低的albuminuria发病率,但这在统计学上并不显著,可能是由于样本大小的限制.
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