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Updated: May 23, 2025

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
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与年龄相关的氧化应激和淋巴结筋细胞中的线粒体功能障碍限制了外围T细胞的恒温维护和功能

Sandip Ashok Sonar1,2, Ruchika Bhat1,2, Heather L Thompson1,2

  • 1Department of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA.

Aging cell
|May 21, 2025
PubMed
概括

衰老会损害淋巴结 (LN) 功能,原因是线粒体功能障碍和 stromal 细胞中的氧化应激. 在老年小鼠中,抗氧化剂治疗恢复了免疫细胞的数量和功能,突出了潜在的治疗点.

关键词:
对于T细胞的恒常性,T细胞的恒常性老化的老化 衰老的老化淋巴结 stromal 细胞是淋巴结的细胞.线粒体功能障碍 线粒体功能障碍氧化应激是一种氧化应激.

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