通过Sim&Size计算的第一线圈和全体体积栓塞比率 (VERs) 的相互依赖性,用于预测动脉瘤闭塞结果
Gianfranco Di Salle1, Alexis Atallah2, Liesjet Eh van Dokkum1
1Neuroradiology Department, Gui de Chauliac, University Hospital Centre of Montpellier, Montpellier, France.
概括
对于内动脉瘤的线圈栓塞需要足够的包装密度来防止复发. 使用体积栓塞比率 (VER) 的虚拟模拟可以优化这种密度,改善长期的闭塞结果.
科学领域:
- 神经外科 神经外科
- 干预性放射学 干预性放射学
- 医疗成像医学成像
背景情况:
- 线圈栓塞是内动脉瘤的标准治疗方法.
- 不充分的包装密度是动脉瘤复发的重要风险因素.
- 识别导致复发的因素对于改善治疗结果至关重要.
研究的目的:
- 为了确定患者和程序相关的因素,与卷轴栓塞后内动脉瘤复发相关.
- 为了评估体积栓塞比率 (VER) 对动脉瘤闭塞的预测值.
- 探索虚拟模拟在优化线圈包装中的作用.
主要方法:
- 以卷轴治疗的79个未破裂的内动脉瘤的回顾性分析.
- 使用Sim&Size®软件计算第一线圈VER和全球VER.
- 多变量分析以确定复发的独立风险因素.
主要成果:
- 在87%的病例中,获得了足够的闭塞 (修改后的Raymond-Roy I-II).
- 下部第一线圈VER和全球VER显著与不充分的闭塞有关.
- 后部位置,动脉瘤高度和部直径也与复发有关.
- 全球VER和第一线VER是复发的独立预测因素.
结论:
- 通过虚拟模拟计算的第一线圈VER和全球VER可以预测栓塞后动脉瘤封闭.
- 优化线圈封装密度,可能由VER指导,可以改善中长期的封闭率.
- 虚拟模拟有望提高线圈栓塞的结果.
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