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Updated: May 23, 2025

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解码Lusichelins A-E:对Lusitaniella coriacea的金属进行深入研究LEGE 07167-结构,生产和功能

Maria Lígia Sousa1, Leonor Ferreira1,2, Dora Ferreira1

  • 1CIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal.

Journal of natural products
|May 21, 2025
PubMed
概括

海洋蓝藻细菌产生新型金属,露西,对于调节铁和铜等重要微量金属至关重要. 这些化合物还显示出针对多药耐药性的癌症治疗潜力.

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Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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