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相关概念视频

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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大脑结构和功能障碍网络定位在强迫症障碍中的定位.

Ya Tian1, Wenqing Shi1, Qiuying Tao1

  • 1From the Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University (Tian, Shi, Tao, Yang, Wen, Wei, Chen, Zhang, Cheng, Han); the Zhengzhou Key Laboratory (Tian, Shi, Tao, Yang, Wen, Wei, Zhang, Cheng, Han); the Henan Engineering Technology Research Center (Tian, Shi, Tao, Yang, Wen, Wei, Zhang, Cheng, Han); the Henan Engineering Research Center (Tian, Shi, Tao, Yang, Wen, Wei, Zhang, Cheng, Han); the Henan Key Laboratory (Tian, Shi, Tao, Yang, Wen, Wei, Zhang, Cheng, Han); the Department of Psychiatry, the First Affiliated Hospital of Zhengzhou University (Guo); the Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China (Chen).

Journal of psychiatry & neuroscience : JPN
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PubMed
概括

强迫症 (OCD) 涉及到大脑网络的广泛变化,而不仅仅是特定区域. 这项研究将这些变化映射到结构和功能网络中,为强迫症提供了对强迫症的新见解.

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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 脑部成像 脑部成像

背景情况:

  • 对强迫症 (OCD) 的神经成像研究显示出不一致的结果.
  • 有证据表明,精神疾病涉及大脑网络,而不是离散区域.
  • 在强迫症中确定大脑网络局部化是至关重要的.

研究的目的:

  • 在强迫症障碍 (OCD) 中识别大脑网络局部.
  • 将强迫症的结构和功能变化映射到特定的大脑网络中.

主要方法:

  • 审查了62项神经成像研究 (2578名强迫症患者,2502名对照).
  • 利用功能连接网络映射 (FCNM) 与大规模的人类大脑连接组数据.
  • 将大脑变化映射到强迫症中两个主要障碍网络.

主要成果:

  • 强迫症障碍网络包括默认模式,感官运动和边缘网络.
  • 双边的中前额和中形旋转都涉及到.
  • 灰色物质体积损伤特别涉及双边下额头.

结论:

  • 集成的FCNM与连接组数据用于绘制强迫症脑网络的地图.
  • 这些发现从网络的角度提高了对强迫症神经病理学的理解.
  • 结果可能会指导未来的神经调制治疗强迫症.