对创伤后应激障碍的创伤重点心理治疗的扩大:系统审查和元分析的协议
Lisa Mewes1,2, Till Langhammer3, Jonathan Torbecke1
1Department of Psychology, Humboldt-Universitat zu Berlin, Berlin, Germany.
BMJ open
|May 21, 2025
概括
本系统性审查审查了治疗创伤后应激障碍 (PTSD) 的创伤重点心理治疗 (TFP) 的非药物增强策略. 它旨在改善患有PTSD的人的治疗结果.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 临床心理学 临床心理学
- 基于证据的实践.
背景情况:
- 创伤集中心理治疗 (TFP) 是对创伤后应激障碍 (PTSD) 的一线治疗方法.
- 有相当数量的个人没有充分受益于或完成TFP.
- 需要增强策略来提高治疗效率并减少PTSD的负担.
研究的目的:
- 系统地审查和元分析随机对照试验 (RCT).
- 评估添加到TFP治疗PTSD的非药物增强策略的疗效.
- 为了比较增强的TFP与单独的TFP或TFP加安慰剂.
主要方法:
- 在多个数据库 (PubMed,Embase,CENTRAL等) 中进行全面的文献搜索. 没有日期或语言限制.
- 独立的选,数据提取,以及由两名审稿人进行偏差风险评估.
- 主要结局 (症状严重程度,反应率) 和次要结局 (退学率) 的叙述综合和元分析.
- 通过子组和元回归分析探索异质性和调节者.
- 使用推评估,开发和评价 (GRADE) 系统进行质量评估.
主要成果:
- 目前正在进行研究选.
- 数据综合和元分析将在选完成后进行.
- 结果将比较增强的TFP和对照条件之间的治疗疗效和放弃率.
结论:
- 这一系统性审查和元分析将提供关于TFP在PTSD治疗中的非药物增强策略有效性的证据.
- 研究结果将为临床实践提供信息,并指导开发增强型PTSD疗法.
- 该研究旨在通过确定更有效的治疗方法来减少PTSD的负担.
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