队列概况:荷兰口腔癌队列
Hanneke Doremiek van Oorschot1,2, Jose Angelito Hardillo3, Robert Jan Baatenburg de Jong3
1Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus MC Cancer Center, Rotterdam, The Netherlands h.vanoorschot@erasmusmc.nl.
BMJ open
|May 21, 2025
概括
荷兰头部和部审计-口腔腔 (DHNA-OC) 收集了2545名口腔癌患者的数据. 这种国家登记册将识别护理的差异,并提高治疗质量.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 口腔癌 (OCC) 的治疗质量和生存率可能会有很大的差异.
- 需要一个全面的国家数据集来评估和基准医疗服务在医疗机构.
研究的目的:
- 建立荷兰头部和部审计-口腔腔 (DHNA-OC) 队列,以研究OCC的护理质量,治疗和生存率.
- 促进对比测试和识别OCC管理中的知识差距.
- 鼓励合作和数据共享,以改善患者的治疗结果.
主要方法:
- 一个基于注册表的2545名首次初级OCC患者的国家队列,在2018年至2021年之间接受了治疗意图的治疗.
- 包括所有14家荷兰医院治疗头癌 (HNC) 的数据,确保全国覆盖.
- 收集有关患者/瘤特征,治疗,并发症,复发和生存的详细变量.
主要成果:
- 诊断时的平均年龄为67岁,大多数瘤处于早期阶段 (cT1: 32%,cT2: 31%).
- 舌头瘤是最常见的;91.3%的患者接受了手术.
- 在晚期瘤阶段的比例中观察到显著的医院变化;数据的完整性很高.
结论:
- DHNA-OC队列为分析OCC的医院变异和治疗效应提供了强大的数据集.
- 未来的研究将重点关注结果指标和基于人群的治疗效应,以确定最佳实践.
- 未来的后续行动和数据收集将继续监测和改善OCC护理质量.
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