在重症儿童中的障碍
Selma Amar1, Sofia Martín Acedo1, Santiago Rodríguez-Tubio2
1Mother and Child and Public Health Department, School of Medicine, Complutense University of Madrid, Madrid, Spain.
Scientific reports
|May 21, 2025
概括
在儿科重症监护室 (PICU) 中,的障碍很常见. 低磁血症与急性损伤,休克,ECMO和严重病症儿童的死亡率增加有关.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 儿科内分泌学 儿科内分泌学
- 儿科脏病学 儿科脏病学
背景情况:
- 对细胞功能至关重要,其干扰经常在重症患者中观察到.
- 了解儿科重症监护中不平衡的患病率和影响对于改善患者的治疗结果至关重要.
研究的目的:
- 确定婴儿重症监护病房 (PICU) 住院儿童中障碍 (低血和高血) 的发生率.
- 调查这些障碍与临床并发症之间的关联,包括急性损伤 (AKI),休克,体外膜氧化 (ECMO) 使用和死亡率.
主要方法:
- 进行了一项单中心,观察性,回顾性研究.
- 血清含量,临床数据,严重程度得分 (FSS,PRISM,P-LOF,P-MODS) 和结果分析了200名进入PICU的儿童.
- 评估了初始和入院低磁血和高磁血的患病率,并与临床参数和结果相关联.
主要成果:
- 低磁血症最初存在于3%的儿童中,并在入院期间存在于13%的儿童中.
- 接受治疗的低磁性血症与AKI (p=0.038),休克 (p=0.003) 和ECMO (p=0.046) 有意义地相关.
- 低磁性血症患者的死亡率较高 (15.4%对1.7%,p=0.006).
- 超血症最初在32%的儿童中被观察到,并在入院期间在44.5%的儿童中观察到.
- 住院高血症与心脏手术相关 (p<0.001),但与死亡率无关 (p=0.702).
结论:
- 障碍,包括低血和高血,在PICU入院中很常见.
- 住院低磁血是重症儿童严重并发症和死亡率的重要预测因素.
- 超血症与心脏手术有关,但似乎不会影响这一队列的死亡率.
相关概念视频
Skeletal Muscle Relaxants: Adverse Effects
327
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Unlike...
327
Mania and Antimanic Drugs: Overview
106
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
106


