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Updated: May 23, 2025

Characterizing Mutational Load and Clonal Composition of Human Blood
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用体内表皮转移进行的克隆追踪揭示了血液衰老的动态

Michael Scherer1,2, Indranil Singh3,4, Martina Maria Braun1,5

  • 1Computational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.

Nature
|May 21, 2025
PubMed
概括

研究人员开发了EPI-Clone,这是一种使用DNA甲基化追踪干细胞分化和身份的无转基因方法. 这种方法可以在小鼠和人类中进行大规模,准确的血系干细胞追踪.

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