开发和验证用于预测癌症患者认知虚弱的诺姆图
Hui Wang1,2, Yu Xia Wu1, Su Yun Dong1
1Department of Oncology, Affiliated Hospital of Nantong University, Nantong, 226001, China.
BMC geriatrics
|May 21, 2025
概括
认知虚弱影响26.7%的老年癌症患者. 一个新的风险模型准确地预测了这种情况,有助于早期临床干预,以获得更好的患者结果.
科学领域:
- 老年瘤学 老年瘤学
- 认知健康 认知健康
- 临床预测建模临床预测建模
背景情况:
- 认知虚弱是老年癌症患者日益关注的问题.
- 早期识别和干预对于管理这一群体至关重要.
研究的目的:
- 为了确定老年癌症患者认知虚弱的患病率.
- 开发和验证这一人口群体认知脆弱性的预测模型.
主要方法:
- 一组308名老年癌症患者被分为培训 (70%) 和验证 (30%) 组.
- 收集的数据包括人口统计,功能状态,营养状况,抑郁症,睡眠质量和认知功能.
- 后勤回归被用来构建一个预测模型,可视化为名图,并使用ROC曲线和校准图表进行验证.
主要成果:
- 在老年癌症患者中,认知虚弱的发生率为26.7%.
- 影响认知脆弱的因素包括低教育水平,抑郁症,睡眠障碍和营养不良.
- 该预测模型的准确性很高,ROC面积为0.934,灵敏度为81.1%,特异性为94.1%.
结论:
- 老年癌症患者受到认知虚弱的显著影响.
- 开发的风险预测模型为早期检测和干预提供了可靠的工具.
- 这种模型可以帮助临床医生积极查和管理这一弱势群体认知脆弱的策略.
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