关于怀孕期间疟疾的最新情况:系统性审查
Awoke Minwuyelet1, Delenasaw Yewhalaw2,3, Melkamu Siferih4
1Department of Biology, College of Natural and Computational Science, Debre Markos University, Debre Markos, Amhara, Ethiopia. awokeminwuyelet5@gmail.com.
Tropical diseases, travel medicine and vaccines
|May 21, 2025
概括
孕期疟疾严重影响母亲和婴儿的健康,导致贫血,低出生体重和增加死亡率. 早期诊断和有效治疗,包括间歇性预防治疗 (IPTp),对于更好的结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 全球健康 全球健康
背景情况:
- 孕期疟疾带来严重的风险,包括孕妇疾病,死亡,贫血,死胎和早产.
- 胎盘寄生虫封存阻碍胎儿生长,导致低出生体重和发育问题.
- 孕期疟疾是围产,新生儿和婴儿死亡率的重要原因之一.
研究的目的:
- 审查怀孕期间疟疾的流行病学模式.
- 评估疟疾对母亲和新生儿健康的影响.
- 分析现有的药物治疗选择及其有效性.
主要方法:
- 在PubMed,Web of Science,Scopus和Pro-Quest的系统文献搜索中搜索英语文章.
- 关键词包括"怀孕中的疟疾"",胎盘疟疾"",先天性疟疾"",治疗选择"和"营养干预和间歇性预防治疗".
- 在排除重复和无关研究后,从4486个已识别的文章中包含了139篇文章.
主要成果:
- 杆菌是非洲并发症的主要原因;P. vivax是一个新兴的全球威胁.
- 在撒哈拉以南非洲,孕妇疟疾的患病率可能高达60%,胎盘疟疾影响高达28%的病例.
- 并发症包括孕产妇贫血,早产,低出生体重和增加孕产妇/婴儿死亡率;像IPTp,ITNs和IRS这样的预防策略至关重要.
结论:
- 怀孕期间的疟疾会导致严重的孕产妇和胎儿不良后果,包括贫血,生长限制,早产和新生儿死亡.
- 患有疟疾的母亲生下的婴儿患疟疾的风险更高.
- 为了在怀孕期间有效控制疟疾,需要进一步的研究和加强治疗策略.
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