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在牙周再生中,雷丁醇增强的PRF与单独的PRF:随机临床试验

Abdallah Hassan^1,2, Weam Elbattawy¹, Dalia Sanaa^1,2

¹Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Journal of periodontal research

|May 22, 2025

概括

维生素A/富血小板纤维素 (VitA/i-PRF) 和i-PRF都改善了牙周缺陷中M-MIST的结果. 最初,VitA/i-PRF在骨再生方面提供了轻微的,不显著的好处,但这种效果在九个月后消失了.

科学领域:

牙周病学牙周病学
再生医学是一种再生医学.
生物材料是一种生物材料.

背景情况:

牙周炎,特别是III级B级的牙周炎,在治疗骨内缺陷方面存在重大挑战.
性粘膜插座道化手术 (M-MIST) 是一种用于牙周再生的技术.
富含血小板纤维素 (PRF) 是一种生物材料,在牙科中被研究其再生潜力.

研究的目的:

为了比较维生素A补充的富含血小板的综合纤维素 (VitA/i-PRF) 与单独的富含血小板的综合纤维素 (i-PRF) 在治疗牙周骨内缺陷的疗效.
评估M-MIST与VITA/i-PRF或i-PRF结合时的临床和放射性结果.

主要方法:

一项涉及患有III期B级牙周炎和牙周骨内缺陷的患者的研究.
使用VITA/i-PRF或i-PRF进行M-MIST程序的应用.
在治疗后6个月和9个月评估临床参数和放射性骨填充.

主要成果:

无论是VITA/i-PRF还是i-PRF组,都显示出临床和放射性结果的改善.
在6个月的随访中,Vita/i-PRF在减少缺陷深度和增加骨填充方面显示出轻微的,但在统计学上并不显著的优势.
观察到的Vita/i-PRF的益处没有持续,在9个月的评估中发现效果正在减弱.

结论:

VitA/i-PRF和i-PRF都有效地改善了M-MIST在牙周内骨缺陷中的结果.
虽然VitA/i-PRF可能在早期骨再生中提供暂时的,无意义的增强,但其长期优势相对于单独的i-PRF在9个月后在临床上并不明显.

关键词:

微创手术是最少的侵入性手术.牙周周节牙周节牙周节牙牙周炎是指牙周炎的一种疾病.富含血小板纤维素的纤维素.一个口袋的口袋.雷丁醇是一种可靠的药物.维生素A是一种维生素A.

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