在患有急性白血病的儿科患者中评估骨矿物质密度
Steve Thomas1, Manoranjan Mahapatra2, Tulika Seth2
1Hematology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|May 22, 2025
概括
儿童白血病患者由于化疗经常患有骨质疏松症和骨质疏松症. 这项研究强调了对接受急性淋巴细胞白血病治疗的儿童的骨矿物质密度和营养状况的监测至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 内分泌学 在内分泌学.
- 代谢性骨疾病 代谢性骨疾病
背景情况:
- 急性淋巴细胞白血病 (ALL) 是一种高度可治愈的儿童癌症.
- 癌症治疗可能会导致不良影响,包括骨健康受损.
- 骨质疏松症是为白血病接受化疗的儿童的一个重大问题.
研究的目的:
- 在接受化疗的白血病儿科患者中评估骨矿物质密度 (BMD).
- 在这个人群中确定骨质疏松症和骨质疏松症的患病率.
- 评估与骨健康相关的营养和生化参数.
主要方法:
- 对患有ALL或急性髓性白血病的儿科患者 (2-20岁) 进行前性观察性研究.
- 数据收集包括基线特征,营养状况和生化标志物.
- 骨矿物质密度 (BMD) 使用双能X射线吸收计 (DEXA) 进行测量.
主要成果:
- 近一半的患者 (46.43%) 患有骨质疏松症,超过四分之一 (28.57%) 患有骨质疏松症.
- 维生素D缺乏 (95.31%) 和其他营养素缺乏的高患病率.
- 低血清白蛋白和维生素D水平是常见的,尽管并不总是统计学上显著的.
结论:
- 儿童白血病患者患有骨质疏松症和骨质疏松症的风险很高.
- 在白血病治疗期间,定期监测骨健康和全面的营养评估至关重要.
- 早期干预和专业护理是必要的,以管理儿童癌症患者的骨并发症.
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