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Updated: May 23, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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机体催化异对称合成的阿扎比赛克洛[2.1.1]hexanes

Layth Alama1, Nils Frank1, Lennart Brücher1

  • 1Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany.

ACS catalysis
|May 22, 2025
PubMed
概括

药物化学家现在可以使用一种新的有机催化方法制造合性azabicyclo[2.1.1]hexanes (aza-BCHs). 这种方法为富含sp3的药物支架提供了模块化和酶选择性合成.

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