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Updated: May 23, 2025

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
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学习利用内部蛋白质3D纳米环境描述器来预测CRISPR-Cas9的目标外活动

Jeffrey Kelvin Mak1, Artemi Bendandi2, José Augusto Salim3

  • 1Department of Computer Science, University of Oxford, Parks Road, Oxford OX1 3QD, United Kingdom.

NAR genomics and bioinformatics
|May 22, 2025
PubMed
概括

研究人员开发了一种机器学习模型STING_CRISPR,用于预测CRISPR-Cas9的脱. 该模型分析了蛋白质的3D纳米环境,以确定影响基因编辑精度的关键因素.

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