整体新辅助疗法与常规新辅助疗法治疗直肠癌:公共卫生保健系统的成本分析
Ishraq Murshed1,2, Sergei Bedrikovetski1,2, Ishmam Murshed1
1Discipline of Surgery, Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia.
ANZ journal of surgery
|May 22, 2025
概括
总的新辅助疗法 (TNT) 对于公共卫生保健系统中的直肠癌患者来说,比传统的新辅助疗法 (CNT) 更具成本效益. TNT显著降低了每位患者的总体成本,主要是由于住院费用较低.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 临床研究 临床研究
背景情况:
- 总的新辅助疗法 (TNT) 越来越多地成为局部晚期直肠癌的标准.
- 与传统的新辅助疗法 (CNT) 相比,TNT 的经济影响仍然被低估.
- 了解成本效益对于公共卫生保健的资源配置至关重要.
研究的目的:
- 为了比较TNT和CNT用于直肠癌治疗的总成本.
- 从第三方付款人的角度分析公共医疗保健系统中的成本差异.
主要方法:
- 根据CHEERS的指导方针进行了基于试验的成本分析.
- 分析了115名用TNT或CNT治疗的直肠癌患者 (2014-2023) 的数据.
- 费用包括住院,门诊,成像和病理学,调整为2024澳元,折扣率为5%.
主要成果:
- 与CNT (140,495.18美元) 相比,TNT (127,138.48美元) 的总体每位患者费用低9.51%.
- 在住院费用方面,TNT显著节省了医疗费用 (78,523.53美元与CNT的96,843.08美元相比).
- TNT导致门诊,成像和病理学成本增加,但这些被住院患者的储蓄所抵消.
结论:
- 总的新辅助疗法 (TNT) 在普遍资助的公共卫生保健系统中,比传统的新辅助疗法 (CNT) 更便宜.
- 与更高的器官保存率相关的降低住院费用是TNT成本效益的主要驱动因素.
- 这些发现支持TNT作为局部晚期直肠癌的经济有利的治疗策略.
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