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Updated: May 23, 2025

Author Spotlight: A Novel Approach to Cerebral Ischemia Modeling – Enhancing Reperfusion and Simplifying Procedure
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对MCP-Mod进行基于随机化的推理

Lukas Pin1, Oleksandr Sverdlov2, Frank Bretz3,4

  • 1MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.

Statistics in medicine
|May 22, 2025
PubMed
概括

这项研究引入了惩罚性最大概率估计 (MLE) 和基于随机化的推断,以改善用小样本的药物试验中剂量选择. 这些方法提高了统计能力,并保持了错误率,为剂量确定分析提供了更好的解决方案.

关键词:
发现剂量发现剂量有限样本推理推理.多个测试多个测试测试.受到惩罚的最大概率估计估计.随机化测试是一种随机化测试.时间趋势 时间趋势

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