创伤后应激障碍及其与艾滋病毒感染退伍军人的发病率和死亡率的关联
Kartavya J Vyas1,2,3,4, Vincent C Marconi2,5,6, Brian K Agan4,7
1Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta.
AIDS (London, England)
|May 22, 2025
概括
创伤后应激障碍 (PTSD) 显著增加了艾滋病毒 (VWH) 的退伍军人的健康风险,特别是在心血管疾病和关节炎等疾病中. 早期创伤知情护理对于管理这些复杂的健康需求至关重要.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 创伤后应激障碍 (PTSD) 是艾滋病毒 (VWH) 的退伍军人关注的一个问题.
- 了解PTSD对VWH健康结果的影响对于退伍军人事务部 (VA) 内的有效护理至关重要.
研究的目的:
- 评估PTSD与各种健康状况 (发病率) 和VWH死亡率之间的关联.
- 确定部署数量和战斗暴露是否会改变这些关联.
- 分析这些关联在艾滋病毒诊断后随着时间的推移而变化.
主要方法:
- 一项前性队列研究包括3206名接受抗逆转录病毒疗法 (ART) 的VWH,他们被部署到伊拉克和阿富汗.
- 后续数据延长至2022年12月,累计超过20,000人年.
- 边际结构性考克斯模型与时间依赖的风险被用于分析.
主要成果:
- 创伤后应激障碍与艾滋病,慢性病,COPD,多病症,心血管疾病和关节炎的风险增加有关.
- 在PTSD和喘,癌症,脑血管疾病,糖尿病,肝脏疾病或全因死亡率之间没有发现显著的关联.
- 创伤后应激障碍对健康风险的影响在诊断后的第一个十年内是最高的,逐渐减少,但仍然很高.
结论:
- 建议对VWH进行创伤信息化的HIV护理模式.
- 建议对退伍军人进行PTSD查,以指导个性化的医疗决策和治疗计划.
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